IMPE Abstracts

A 9 - year-old boy was referred to our hospital because of precocious puberty. At the first visit, thyroid function test was performed using electrochemiluminescent immunoassay (ECLIA) and the serum TSH level was markedly elevated (32.30 μIU/mL), but the serum level of free T4 was within the reference interval. Anti-thyroid antibodies were negative and thyroid ultrasonography was normal. He diagnosed as central precocious puberty, but no clinical symptom of hypothyroidism. ...

Mother who began her illness at the age of 32 years with progressive weakness of extremities, weight loss and dysarthria, diagnosed 1 year later with metastatic medullary thyroid cancer, by DNA analysis of peripheral blood leukocytes (TGC-TGG mutation in codon 634 of the RET gene). A genetic study was performed in the family branch (3 children), with the result of heterozygous mutation in codon 634 of the RET proto-oncogene in 2 children of 11 and 5 years of age. Patient 1: Ma...

Introduction: Slipped capital femoral epiphysis (SCFE) represents a spectrum of diseases with variable presentation and symptoms, chronicity, deformity, and long-term sequelae. Multiple primary endocrine abnormalities have been associated with the development of SCFE, such as hypothyroidism, hyperparathyroidism, renal osteodystrophy, and growth hormone deficiency, which involve, in most cases, atypical presentations of this disease, without the classic clinica...

Background and Aims: Whether as a cause or consequence, thyroid dysfunction is associated with overweight and obesity. There is limited data on radiological assessment of thyroid glands in obese patients. The present study was conducted to measure the radiological changes in thyroid glands in overweight/obese children.Methods: This case-control study enrolled forty overweight/obese children (5-18 years) and compared with...

Introduction: Thyroid cancer is a rare disease in children. Malignancy should be suspected in the presence of non-infectious cervical adenopathy, a palpable thyroid nodule, or an asymmetric thyroid gland. Risk factors associated with developing follicular thyroid cancer include autoimmune thyroid disorders, iodine deficiency, and prior exposure to radiation.Case report: A 6-year-old male patient was evaluated at the pedi...

Fetal goiter is an extremely rare complication of pregnancy, presenting with a fetus with hypo or hyperthyroidism. A 24-year-old woman with a history of subclinical hypothyroidism at 6 weeks gestation and treated with levothyroxine was referred to our hospital at 22.5 weeks gestation with a report of an anterior cervical mass of 3.4 cm x 1.3 cm found on her structural ultrasound. Her last TSH was 4.38 uUI/mL, free T4 1.15 ng/dL. An MRI was performed at 26 weeks gestation, repo...