IMPE Abstracts

Introduction: Type 2 diabetes (T2D) is increasing among adolescents and is associated with suboptimal mental health. Diabetes-specific distress (DD) is common in adolescents with Type 1 diabetes but there is limited data in adolescents with T2D. Additionally, data in relation to how clinicians can better support the emotional wellbeing and engage adolescents with T2D is limited to Indigenous adolescents.Aims: To evaluate...

Objective: Identify the factors association with the serum level of RIAO (real IAPP amyloid oligomers) <3.02 μg/ml at the diagnosis of the DM2 as a predictor of development of chronic complications in children and adolescents.Type of study: Historical cohort, observational, longitudinal, futurology, comparative,Materials and methods: The DM2 patients with determinations of RI...

Background: Neuregulin-4 (Nrg4), a recently identified adipokine, has been found in multiple organs, in particular brown adipose tissue. Lower Nrg4 levels have been associated with obesity, insulin resistance, impaired glucose tolerance and type 2 diabetes mellitus (T2DM). Metformin is widely utilized for treatment of T2DM due to its ability to improve glycemic control. It has shown some potential in preclinical studies to improve diabetic nephropathy, decreas...

Introduction: Diabetes represents a heterogeneous group of metabolic disorders, and monogenic diabetes is thought to affect 1- 5% of the pediatric diabetes population. Monogenic diabetes, typically presenting without autoimmune antibodies, causes neonatal diabetes, maturity-onset diabetes of the young (MODY), and syndromic diabetes. The study aimed to gain insight into the gene regulation pathways altered in MODY diabetes following a meal.<p class="abstext...