IMPE Abstracts

Background: The etiological investigation of central precocious puberty (CPP) has improved with more precise clinical approach, neuroimaging, and genetic studies. CPP can be caused by congenital or acquired conditions, with or without central nervous system (CNS) lesions. More recently, genetic and epigenetic disorders have been identified in children with CPP, previously classified as idiopathic.Objective: To update the...

Introduction: Self-limited delayed puberty is defined as the absence of pubertal signs by 13 years in girls and 14 years in boys, but with normal pubertal development starting before 18 years of age. This condition is known for its strong heritability. This study aimed to identify new candidate genes for pubertal delay.Methods: Fifty-six patients with confirmed self-limited delayed puberty after retrospective evaluation ...

Background: Although previous studies suggested that there is a certain level of body fat mass before puberty can be initiated, most studies have focused on girls.Objective: To investigate the relationship between precocious puberty and physical growth in school-aged children in Beijing, China.Methods: 7590 Chinese children (3591 girls and 3999 boys) aged 6–11 years were recr...

Background: There are limited studies of growth and growth velocity (GV) after discontinuation of GnRHa in ICPP girls. Controversy exits about the growth after GnRHa especially regarding age of onset/end of treatment and onset of menses.Objective: To evaluate growth after GnRHa discontinuation up to final height (FH) by growth velocity analysis (GV), time of menarche (TM) and change of standard deviation of height for bo...