IMPE Abstracts

Objective: Type 1 diabetes mellitus (T1D) incidence in children varies across regions and countries. A large incidence increase has been observed in several countries during the COVID-19 pandemic. The objective of this study is to determine the trends in T1D incidence rates in Chilean children between 2006 and 2021, and specifically evaluate the effect of COVID-19 pandemic in this population.Methods: We reviewed mandator...

Introduction: Central precocious puberty (CPP), the development of secondary sex characteristics before ages 8 and 9 years in girls and boys, is caused by premature activation of the hypothalamus-pituitary-gonadal (HPG) axis. A gonadotropin-releasing hormone stimulation (GnRH test) is the gold standard diagnostic method to confirm activation of the HPG axis and peak LH levels higher than 5 IU/L are considered a pubertal response. However, the GnRH test is expe...