IMPE Abstracts

Background: Guidelines for safe fasting strategies exist for both adolescents and adult patients living with type 1 diabetes (T1DM). Management of T1DM during fasting is complex, however, strategic approaches including insulin adjustments, education, and nutritional modifications to reduce the likelihood of hypoglycemia.Aim: This prospective study assessed the safety and effectiveness of an advanced hybrid closed-loop (A...

Background: Neuregulin-4 (Nrg4), a recently identified adipokine, has been found in multiple organs, in particular brown adipose tissue. Lower Nrg4 levels have been associated with obesity, insulin resistance, impaired glucose tolerance and type 2 diabetes mellitus (T2DM). Metformin is widely utilized for treatment of T2DM due to its ability to improve glycemic control. It has shown some potential in preclinical studies to improve diabetic nephropathy, decreas...