IMPE Abstracts

Objective: The growth plate is the metabolically highly active cartilage portion of the bone where linear growth takes place. Chondrocytes in this region are affected by many hormones and local factors in the process of proliferation, maturation, hypertrophy, extracellular vesicle release and cell death. Melatonin, one of these factors, affects blastic activity, proliferation and mineralization in a circadian rhythm through its receptors in cartilage. In the g...