IMPE Abstracts

Tolvaptan, a V2-receptor antagonist, is used for the treatment of chronic hyponatremia in adult patients with syndrome of inappropriate antidiuretic hormone secretion (SIADH). However, its use in children has not been established. Here we present a child case of chronic SIADH successfully treated with tolvaptan. The patient is a 5-year-old boy with congenital intracranial teratoma, complicated with hydrocephalus and severe motor and mental retardation. He has combined central ...

Congenital Lipoid Adrenal Hyperplasia (CLAH) is the most severe form of congenital adrenal hyperplasia. It is caused by mutation in the steroidogenic acute regulatory protein (StAR) gene, which can be of autosomal recessive inheritance. A 6-year-old girl, with a background of recurrent febrile seizure, presented with history of seizure, preceded by 1-day history of fever. On presentation, she had reduced consciousness, hypoglycemia with refractory hypotensive shock. She was in...