Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

impe0096p63 | Fat, Metabolism and Obesity | IMPE2023

Secular trends in obesity and dyslipidemia in 10-year-old children: a long-term epidemiological survey over 27 years in Oita City, Japan

Maeda Miwako , Maeda Tomoki , Ihara Kenji

Background: Domestic and international epidemiological studies have reported that childhood obesity and serum lipids were associated with lifestyle-related diseases in adulthood. There are few long-term epidemiological studies on the relationship between serum lipids and obese in Japanese children.Purpose: Based on the data Oita City schoolchildren lifestyle-related disease screening program (height, weight, serum total ...

impe0096p44 | Diabetes and Insulin | IMPE2023

Long-term trends of pediatric type 1 diabetes incidence in Japan: before and during the COVID-19 pandemic years (1999–2021)

Matsuda Fumika , Itonaga Tomoyo , Maeda Miwako , Ihara Kenji

Background: The incidence of type 1 diabetes has increased worldwide whereas a long-term trend for pediatric type 1 diabetes has remained elusive in Japan. Because a nationwide registry system for pediatric type 1 diabetes has not been established in Japan, it is difficult to simply extrapolate a national epidemiological study from the MAPChD data in Japan. The local registry systems in each prefecture or small-scale adjacent areas would be better for extracti...

impe0096p54 | Fat, Metabolism and Obesity | IMPE2023

The stability of amino acids, free and acyl-carnitine in dried blood specimens stored after newborn screening

Shimada Yumi , Kawano Nanae , Goto Miho , Watanabe Hiromi , Ihara Kenji

Background: Inborn errors of metabolism (IEM) are a consequence of genetic defects that lead to a metabolic block in a biochemical pathway critical to tissue-specific cellular functions. Prompt and effective intervention in screening-positive patients is particularly important in cases of IEM. Newborn mass screening has developed aiming to identify newborns who appear healthy but who could be at risk of developing metabolic attacks with the potential to lead t...

impe0096p61 | Fat, Metabolism and Obesity | IMPE2023

Sarcopenia in children with acute leukemia was worsened after induction therapy

Itonaga Tomoyo , Matsuda Fumika , Hirano Naoki , Maeda Miwako , Suenobu Souichi , Ihara Kenji

Background: Sarcopenia is a common disorder among elderly people defined by the loss of skeletal muscle mass accompanied by a physical function disorder. In recent years, it has been reported that the loss of skeletal muscle mass is a poor prognostic factor in pediatric cancer patients as well as adult cancer patients. In the elderly, a decrease in IGF-1 was suggested to be one of the responsible factors in the development of sarcopenia, but there have been no...