Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

impe0096p72 | Fetal, Neonatal Endocrinology and Metabolism | IMPE2023

Does iodine excess affect fetal thyroid gland differently in early gestation? A prospective study on the impact of oil-soluble contrast hysterosalpingography on offspring’s thyroid function

Mathews Divya , Peart Jane , Sim Robert , O'Sullivan Susannah , Derraik José , Heather Natasha , Webster Dianne , Johnson Neil , Hofman Paul

Background: Hysterosalpingography (HSG) using oil-soluble contrast medium (OSCM) improves fertility with pregnancy rates of approximately 40% reported in women within six months of the procedure. However, OSCM has high iodine content and long half-life resulting in severe and persistent maternal iodine excess for up to 6 months. Any fetus conceived during this time would be exposed to a high iodine load with the potential for thyroid dysfunction from the Wolff...