IMPE Abstracts

Background: Autoimmune polyglandular syndromes are rare in children. APS-1 typically presents in childhood and adolescence, is due to mutation in AIRE gene. APS-2 typically presents in adolescence and adulthood, is polygenic in nature. Myasthenia gravis is an autoimmune disorder characterized by neuromuscular weakness, fatigue, due to autoantibodies toward acetylcholine receptor. The association of myasthenia gravis with other autoimmune diseases is well known...