Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

impe0096p17 | Bone, Growth Plate and Mineral Metabolism | IMPE2023

Association of Trabecular Bone Score and Bone Mineral Apparent Density with the Severity of Bone Fragility in Children and Adolescents with Osteogenesis Imperfecta: A Cross-sectional Study

Ohata Yasuhisa , Kitaoka Taichi , Ishimi Takeshi , Yamada Chieko , Nakano Yukako , Yamamoto Kenichi , Takeyari Shinji , Nakayama Hirofumi , Fujiwara Makoto , Kubota Takuo , Ozono Keiichi

Osteogenesis imperfecta (OI) is a hereditary skeletal disease characterized by bone fragility. Bone mineral density (BMD), evaluated by dual-energy X-ray absorptiometry (DXA), is used to assess bone brittleness. The height-for-age Z-score (HAZ)-adjusted BMD-for-age Z-score (BMDHAZ) to reduce the confounding factor of short stature is calculated in children and adolescents with OI. However, even with BMDHAZ, severity evaluation in children and adolescents ...