impe0096fc16.2 | Thyroid 2 | IMPE2023
Nichols Presley
, Tillotson Cara
, Rahming Virginia
, Steinman Jonathan
, Thaker Vidhu
, Oberfield Sharon
, Vuguin Patricia
, Torres Alejandro
, N Ham Jee-Young
In the setting of iodine excess, organification of thyroglobulin is blocked, serving as a protective mechanism against hyperthyroidism. This phenomenon, the Wolff-Chaikoff effect, can result in persistent hypothyroidism. Excessive iodine exposure is usually iatrogenic, coming in the form of radiographic dyes, amiodarone, and povidone-iodine antiseptic solution. In March 2022, the US Food and Drug Administration (FDA) released a statement that at-risk children up to age 3 years...