impe0096fc5.3 | Fat, Metabolism and Obesity | IMPE2023
L. Roth Christian
, S. Chichura Kylie
, R. Sweet Ian
, Elfers Clinton
, Berry Dustin
, T. Milliken Brandon
, P. Doyle Robert
Mechanisms underlying long-term sustained weight loss and glycemic normalization after obesity surgery involves changes in gut hormone levels, including glucagon-like peptide 1 (GLP-1) and peptide YY (PYY). Designing dual or triple agonists based on glucagon-like peptide (GLP)-1 with glucagon, and/or glucose-dependent insulinotropic polypeptide (GIP) are promising novel approaches for anti-obesity drugs tackling different weight-regulatory pathways, albeit such developments co...