IMPE Abstracts

Introduction: Neurogenin-3 (NEUROG3) is a key transcription factor expressed in endocrine progenitor cells and is necessary for the development of endocrine cells in the pancreas and intestine. Its homozygous pathogenic variants cause an autosomal recessive disorder characterized by congenital malabsorptive diarrhea due to paucity of enteroendocrine cells and diabetes which occurs from the neonatal stage to school age.Objectives:...