IMPE Abstracts

Introduction: McCune Albright syndrome is diagnosed by classical clinical manifestations of cafe au lait skin macules, multiple endocrinopathies and fibrous dysplasia of bones. The prevalence of syndrome is estimated at 1 in 100,000 to 1 in 100,000,000. McCune Albright syndrome is caused by a postzygotic mutation of the GNAS gene, which results in great variability in clinical presentation. The most common endocrine manifestation is premature puberty, but hype...