Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

impe0096p71 | Fetal, Neonatal Endocrinology and Metabolism | IMPE2023

Continuous intravenous glucagon in children with congenital hyperinsulinism: A retrospective single center evaluation of effects and adverse effects

Husnan Ahmad Jonas , Bygum Anette , Hallas Jesper , Vasilescu Ilieana , Stenbakken Nielsen Peter , Thybo Christesen Henrik

Background: Congenital hyperinsulinism (CHI) is characterized by hyperinsulinemic hypoglycemia, conferring a high risk of neurodevelopmental impairment if not treated promptly and sufficiently. The conventional medications are often ineffective and while some forms of CHI are curable by surgery, new treatment modalities are advocated. Glucagon counteracts the action of insulin, but the use in CHI has been limited. We aimed to evaluate the efficacy and side eff...