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impe0096p100 | Growth and Syndromes | IMPE2023

The Impact of Delaying Pubertal Development on Height Gain and Near Adult Height in Short Children born Small for Gestational Age (SGA) treated with Growth Hormone

Lanes Roberto , Ove Carlsson Martin , Rooman Raoul , Gomez Roy , Wajnrajch Michael

Context: Growth hormone (rhGH) treatment has been shown to be effective in improving growth velocity and the adult height (AH) of short children born SGA if started early on. It is less effective when used to treat short SGA adolescents, as some fail to exhibit catch-up growth.Objective: The primary objective of this study was to evaluate the impact of Gonadatropin Releasing Hormone analogues (GnRHa), in addition to rhGH...

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impe0096ep43 | GH and IGFs | IMPE2023

Daily growth hormone adherence and height velocity in children with pediatric growth hormone deficiency (pGHD) from a single-center institution in Minnesota, USA

S Miller Bradley , Loftus Jane , Kelkar Mona , Shrestha Swastina , Parzynski Craig , Benjumea Darrin , Wogen Jenifer , Jhingran Priti , Alvir Jose , Gupta Anu , Wajnrajch Michael

Background: Pediatric growth hormone deficiency (pGHD) is treated with daily somatropin (recombinant human growth hormone) injections. High discontinuation rates and poor adherence to treatment, which may be associated with worse growth outcomes, have been documented in Japan, EU and the US.Objectives: To describe adherence to daily somatropin treatment and assess the association between adherence and height velocity (HV...

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IMPE Abstracts

The Impact of Delaying Pubertal Development on Height Gain and Near Adult Height in Short Children born Small for Gestational Age (SGA) treated with Growth Hormone

Daily growth hormone adherence and height velocity in children with pediatric growth hormone deficiency (pGHD) from a single-center institution in Minnesota, USA

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