Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

impe0096p67 | Fetal, Neonatal Endocrinology and Metabolism | IMPE2023

Hematocrit correction: impact on neonatal screening (NS) for endocrinopathies

Marino Silvia , Tommasi Florencia , VilcheJuarez Alejandro , Belen Alvarez Olmedo Maria , Arias Christian , Zeida Gerard , Dratler Gustavo

Hematocrit was considered an uncontrollable variable that affects results of biomarkers in whole blood filter paper samples (FPS). NS methodologies are generally adjusted by assuming a standard hematocrit of 55%. Our group has previously presented a method to estimate hematocrit by measuring hemoglobin values in FPS. This correction has the potential to reduce the number of false positives, improve specificity in NS, and decrease the number of recalled patients.<p class="a...