Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

IMPE Abstracts

Published by BioScientifica
Volume 96 | IMPE2023

IMPE 2023

Buenos Aires, Argentina
04 Mar 2023 - 07 Mar 2023

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11th International Meeting of Pediatric Endocrinology (IMPE 2023). 4 -7 March 2023 - Buenos Aires, Argentina.

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Thyroid 1

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impe0096fc8.1 | Thyroid 1 | IMPE2023

ABSTRACT WITHDRAWN...
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impe0096fc8.2 | Thyroid 1 | IMPE2023

Overexpression of Brachyury and IGF1R in Thyroid Papillary Carcinoma cells: different phenotypes and asocciation with pediatric Thyroid Nodular Pathology

Martin Ayelen , Celia Fernandez María , Miraglia Sofía , Medín Martín , Papendieck Patricia , Clément Florencia , De Matteo Elena , Chiesa Ana , Pennisi Patricia

In pediatrics, thyroid tumor stratification is difficult to assess. Epithelial-mesenchymal transition (EMT), plays a role in tumor development. In human carcinomas Brachyury (Brachy) has been identified as a regulator of EMT associated to malignancy. The Insulin Like Growth Factors (IGFs) are mitogens that play important roles in both normal and neoplastic growth. To date, no information about Brachy and IGF1R expression in pediatric thyroid nodular disease is available.<p...
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impe0096fc8.3 | Thyroid 1 | IMPE2023

Sensitivity to thyroid hormones and cardiometabolic risk in euthyroid obese children: a cross-sectional study.

Wasniewska Malgorzata , Tropeano Angelo , Corica Domenico , Curatola Selenia , Li Pomi Alessandra , Alibrandi Angela , Pepe Giorgia , Aversa Tommaso

Background: The typical biochemical phenotype related to obesity, that is high serum TSH within normal range, low/normal free thyroxine (FT4) and increased free triiodothyronine (FT3) levels, can be interpreted as a resistance to thyroid hormones. It is unclear the role played by thyroid hormones in the pathogenesis of metabolic derangement associated with obesity.Aim: To investigate the association between thyroid hormo...
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impe0096fc8.4 | Thyroid 1 | IMPE2023

Custom next generation sequencing panel identifies somatic mutations and gene fusions in pediatric papillary thyroid carcinoma

Ramirez Pablo , Perez Garrido Natalia , Dujovne Noelia , Gazek Natalia , Trobo Sofia , Saraco Nora , Juanes Matias , Garcia Francisco , Aschettino Giovanna , Lopez Marti Jessica , Herzovich Viviana , Belgorosky Alicia , Marino Roxana

Thyroid cancer is rare in childhood accounting for 0–3% of all pediatric malignancies. Children with thyroid cancer demonstrate higher rates of cervical lymph node involvement and pulmonary metastases, the long-term outcome is rather favorable and mortality rate is low compared with adults. An increasing incidence of the disease has been observed in the last years. There is not enough evidence about the molecular mechanisms implicated and the correlation with prognosis a...
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