IMPE2023 Poster Presentations Diabetes and Insulin (16 abstracts)
IMPACT of Type of Treatment on Health-Related Quality of Life in Children and Adolescents with T1D. A Multicenter Study in LIMA, Perú
Mónica Julissa Angulo Barranca 1 , Sheyla Paola Alegre Pariona 2 , Nátaly Claudia Aramburú Miranda 2 , Ana Cecilia Bonilla Suárez 2 , Melissa Maricela Martinez Peralta 2 , Cecilia Pinto Paz 3 , Luciana Scerpella Crespo 4 & Alejandro Isaias Angulo Quispe 5
1CREDIN, Lima, Peru. 2Instituto Nacional de Salud del Niño San Borja, Lima, Peru. 3Hospital Cayetano Heredia, Lima, Peru. 4Clinica Anglo Americana, Lima, Peru. 5Universidad Nacional Luis Gonzaga, Ica, Peru
Type 1 Diabetes Mellitus (T1D) is a chronic illness that impacts the quality of life (QoL) of patients and their families. Currently, different methods exist that facilitate glycemic control and insulin administration to achieve good metabolic control, which may contribute to a better QoL. Perú is a middle-income country with low prevalence of T1D and low access to diabetes technology. We evaluated the QoL in children and adolescents with T1D using different methods of metabolic control in different health centers in Lima, Perú.
Materials and methods: Retrospective descriptive study in children and adolescents with T1D from 4 health care centers in Lima. We included patients from 4-18 years with 1 year since T1D diagnosis. Patients where stratified in four groups according to insulin therapy and glucose monitoring: group 1 multiple day injection (MDI) with human insulins and glucometer; group 2 MDI with insulin analogs and glucometer; group 3 MDI with insulin analogs and continuous glucose monitoring (CGM); group 4 insulin pump therapy (ISCI). We used Peds-Ql 3.0 survey to assess QoL in T1D in patients and their main caregiver. Clinic and demographic characteristics of the last year were collected. SPSS 24.0 was used for statistical analysis.
Results: 42 patients were included with a mean age of 12.83 years (42.9% men and 57.1% women), a mean disease time of 4.16 years and mean HbA1c of 8.6%. Comorbidities where present in 14.3% patients, 45.2% presented hypoglycemia and 9.5% ketoacidosis. Only 11% of patients used ISCI for insulin administration and 52% used CGM for glucose control. Mean QoL and SD are shown in table 1. Patients with higher HbA1c had lower scores in QoL.
| n (42) | QoL Caregivers Mean and SD | QoL Patients Mean and SD | |
| Group 1 | 7 | 42,98 ± 8,05 | 48,47 ± 4,95 |
| Group 2 | 8 | 56,92 ± 11,51 | 60,46 ± 13,13 |
| Group 3 | 22 | 58,44 ± 10,08 | 60,23 ± 12,62 |
| Group 4 | 5 | 67,86 ± 3,68 | 69,20 ± 0,89 |
Conclusions: This study suggests that perception of QoL is lower in patients and caregivers who use MDI and glucometer compared to CGM and ISCI. Diabetes access to technology might have a positive impact in QoL of patients and their families.
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