IMPE Abstracts

The purpose of the study was consisted in evaluating the general clinical laboratory characteristics of children using insulin degludec. Material and methods: 42 children with type 1 diabetes mellitus were monitored. Blood glucose and glycohemoglobin were determined by laboratory methods. Statistical calculations were analyzed using Statistica 14.0 statistical software. Results and their discussion: the average age of the examined children was 11.4±4.07 years, the duration of the disease was 5.1±3.75 years, the average dose of aspart was 22.4±10.6 units, and the average dose of degludec was 13.6±6.49 units, the average value of blood glucose was 209.9±138.35 mg/dl, and the average value of glycohemoglobin was 9.8±2.34%. The correlation between the indicators of children using degludec was studied. Positive correlation was found between dose of degludec and body weight (r=0.91, P≺0.05), height (r=0.79, P≺0.05), dose of aspart (r=0.86, P≺0.05). There was no correlation with dose of decludec between blood glucose (r=0.17, P≻0.05), glycohemoglobin (r=0.23, P≻0.05), age (r=0.46, P≻0, 05). There was a positive relationship between aspart and body weight (r=0.81), height (r=0.56), blood glucose (r=-0.11, P≻0.05), glycohemoglobin (r=0.04, P≻0.05) and age (r=0.18, P≻0.05) correlation was not found. The result: insulin degludec and aspart were positively correlated with body weight and height.