IMPE Abstracts

Objective: To describe the appendicular skeleton strength (ASS) and the associate factors in adolescent with diabetes mellitus

Methodology: Cross-sectional study in puberal patients (9 to 18 years) with DM. By means of clinical records review, we corroborated demographic, auxology and biochemical variables as well as the presence or not of complications. Body Satisfaction Discomfort (BSD) was evaluated using Stunkard silhouettes, BMD, corporal composition and ASS across the whole body (WB), lumbar spine (LS) and hip was measured using dual energy X-ray absorptiometry (DXA). We utilized the statistical software package of JMP 11.

Results: 28 patients were analyzed, 42% male, 20 patient with T1DM and 8 with T2DM, mean age 14.3 years, BMI Z score 0.36, HbA1c 8.4 ± 2.35%. ASS in female patients with type 1 DM was significatively lower (5.17 ± 1.16 vs 7.17 ± 1.87 Kg/m2, P= 0.049), while the male patiennts with type 2 diabetes had lower ASS (6.35 ± 1.11 vs 7.17 ± 0.76, P= 0.047): The ASS in all the patients had positive correlations with the index free fat mass, leg circumference, age, BMD of femoral neck and osteocalcin. We observe negative correlation with BSD, HbA1c. HDL-C y waist/hip ratio.

Conclusions: Girls with type 1 diabetes and boys with type 2 DM have lower ASS. Patients with BSD we identified lower ASS associate with lower mineral density in the femoral neck. This justify the importance of measuring ASS as an indicator of sarcopenia associated with lower BMD and BSD in patients with DM to evaluate bone health and intervention on healthy lifestyle habits.