Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

impe0096p145 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | IMPE2023

Identification of The Minimum Dose of Human Chorionic Gonadotropin Hormone to Generate Positive Response in Patients with Differences in Sexual Development at The National Institute of Pediatrics in The Period 1990-2020

Mamani Molina Roly , de la Luz Ruiz Reyes María , Altamirano Bustamante Nelly , Calzada León Raúl

Introduction: To assess testicular function, in patients with differences in sexual development (DSD), the Leydig cell stimulation test with human chorionic gonadotropin hormone (hCG) is performed and testosterone production is measured. There is no uniformity in terms of hCG dose or duration of stimulation. At the National Institute of Pediatrics (INP), this test is performed with 10,000 IU IM, for 4 consecutive days, and a daily sample of testosterone is tak...

impe0096ep83 | Thyroid | IMPE2023

Familial medullary thyroid carcinoma, case report

Torres Vallejo Andrea , Elesva Guadarrama Zenteno Saira , Francisca Altamirano Bustamante Nelly , de la Luz Ruiz Reyes María , Calzada León Raúl

Mother who began her illness at the age of 32 years with progressive weakness of extremities, weight loss and dysarthria, diagnosed 1 year later with metastatic medullary thyroid cancer, by DNA analysis of peripheral blood leukocytes (TGC-TGG mutation in codon 634 of the RET gene). A genetic study was performed in the family branch (3 children), with the result of heterozygous mutation in codon 634 of the RET proto-oncogene in 2 children of 11 and 5 years of age. Patient 1: Ma...

impe0096fc11.2 | Diabetes and Insulin 1 | IMPE2023

RIAO as an early biomarker of β-cell failure and predictor biomarker of metabolic syndrome

Altamirano-Bustamante Nelly , Belén Mosquera-Andrade María , Castillo Monica , Angel Blanco Miguel , Gonzàlez Alejandro , Revilla-Monsalve Cristina , Garrido Eulalia , Calzada-León Raul , M Altamirano Bustamante Myriam

Objective: Identify the factors association with the serum level of RIAO (real IAPP amyloid oligomers) <3.02 μg/ml at the diagnosis of the DM2 as a predictor of development of chronic complications in children and adolescents.Type of study: Historical cohort, observational, longitudinal, futurology, comparative,Materials and methods: The DM2 patients with determinations of RI...

impe0096p155 | Thyroid | IMPE2023

Prognostic factors in papillary thyroid cancer, experience in a third level care hospital.

Torres Vallejo Andrea , Elesva Guadarrama Zenteno Saira , Janeth Castillo Urias Mónica , Cámara Corona Eduardo , Cecilia Massuh Coello María , Francisca Altamirano Bustamante Nelly , de la Luz Ruiz Reyes María , Calzada LeónW Raúl

Introduction: Papillary thyroid cancer represents the eighth most frequent neoplasm in pediatrics. In the Instituto Nacional de Pediatría it is the most frequent endocrine neoplasm commonly associated with other thyroid disease.Objective: To evaluate the association between papillary thyroid cancer and risk factors such as sex, autoimmune thyroiditis, history of neoplasia and radiation.<stro...

impe0096fc14.3 | Miscellaneous Growth | IMPE2023

Possible triggers related to the increased frequency of Idiopathic Central Precocious Puberty during and after COVID-19 confinement at the National Institute of Pediatrics in Mexico.

Elesva Guadarrama-Zenteno Saira , Torres-Vallejo Andrea , Cámara-Corona Eduardo , Janeth Castillo-Urias Mónica , Cecilia Massuh-Coello Maria , Lucía Reyes-López Ana , Francisca Altamirano-Bustamante Nelly , de la Luz Ruiz-Reyes María , Lissette Arguinzoniz-Valenzuela Sletza , Calzada-León Raúl

Introduction: A significant increase in the incidence of precocious puberty secondary to the COVID-19 pandemic has been demonstrated worldwide. This phenomenon appears to be related to lifestyle changes forced by confinement.Objective: To perform a retrospective evaluation of newly diagnosed idiopathic central precocious puberty (ICPP) during and after COVID-19 confinement at the National Institute of Pediatrics (NIP), c...