IMPE Abstracts

Thyroid cancer is rare in childhood accounting for 0–3% of all pediatric malignancies. Children with thyroid cancer demonstrate higher rates of cervical lymph node involvement and pulmonary metastases, the long-term outcome is rather favorable and mortality rate is low compared with adults. An increasing incidence of the disease has been observed in the last years. There is not enough evidence about the molecular mechanisms implicated and the correlation with prognosis a...

Growth is influenced by genetic, nutritional, environmental, and hormonal factors, but it proceeds in a remarkably predictable pattern characterized by a constant growth deceleration between childhood and adolescence, when the pubertal growth spurt occurs. This growth deceleration is coordinated in multiple tissues and organs in order to maintain body proportions. Growth hormone (GH)/ insulin-like growth factor type 1 (IGF1) axis and insulin are crucial stimulators of growth, ...