IMPE Abstracts

Cushing’s syndrome (CS) is a rare pediatric endocrine disorder. Most cases originate from pituitary lesions and less than 1% are caused by ectopic ACTH-secreting tumors. A previously healthy 9-year-old girl developed abrupt weight gain, Cushingoid phenotype, and behavior changes over 5 months. Subsequently, she developed fever, diarrhea, abdominal pain, abnormal gait, and myalgia. She was admitted to a local hospital with symptomatic hypokalemia requiring IV potassium co...

Introduction: Children with steroid-resistant nephrotic syndrome (SRNS) are at high risk of developing hypothyroidism due to the urinary loss of serum (s) thyroid hormone-binding proteins, thyroxine (T4) and triiodothyronine (T3). There are limited data on the variability in thyroid hormone profiles and replacement doses in pediatric SRNS.Aims: To analyze the thyroid hormone profile in pediatric patients with SRNS under ...

Introduction: Cushing's disease (CD) in the context of chronic kidney disease (CKD) is very rare. CKD causes physiological hypercortisolism making the diagnosis of CD extremely difficult.Aim: To report 3 female patients with CKD and CD and to outline the principles that may guide the diagnosis of CD in this context.Case report: P1. A 12.3-year-old patient with CKD secondary to...