impe0096fc7.4 | Bone and Growth | IMPE2023
Loscalzo Emely
, See Julia
, Bharill Sonum
, Yousefzadeh Nazanin
, Gough Ethan
, Wu Malinda
, Crane Janet
Duchenne and Becker’s Muscular Dystrophy are X-linked progressive muscular disorders caused by mutations in dystrophin, leading to progressive muscle weakness. Glucocorticoids prolong ambulation and lifespan but cause significant endocrine complications. We assessed the prevalence of growth impairment, pubertal delay, and osteoporosis, along with the impact of growth hormone (GH), testosterone, and/or bisphosphonate in a longitudinal study of 27 males with dystrophinopat...