IMPE Abstracts

The adrenal cortex undergoes constant cellular turnover: capsular stem cells give rise to cortical progenitor and differentiated steroidogenic cells of the zona glomerulosa (zG). Despite knowledge of their existence, little is known about these progenitor populations and have not previously been identified in single cell RNA sequencing (scRNA-Seq) transcriptomic analysis. We postulated that additional ACTH stimulation in the context of 21-hydroxylase deficiency may affect the ...