IMPE Abstracts

Diabetes insipidus (DI) is characterized by polydipsia and polyuria with a dilute urine. Central DI (CDI) results from a deficiency of arginine vasopressin (AVP) and may be due to congenital or acquired causes, the latter include tumors affecting the hypothalamic-pituitary region. Thirst acts as a central biological backup mechanism in the absence of AVP, allowing plasma osmolarity to remain stable. We describe ADI patients with hypothalamic damage, who lose the ability to per...