IMPE Abstracts

Background: Recent research has indicated an association between patients with CAH and higher incidence of obesity associated with cardiovascular risk. Individuals with congenital adrenal hyperplasia suffers from 21-hydroxylase deficiency, which leads to lack of cortisol and aldosterone, causing androgen excess. Early diagnosis and treatment are essential to prevent morbidity and mortality, both of which are increased on CAH patients in comparison to populatio...

Monogenic obesity is a rare, severe condition, associated with early-onset weight gain. In the last years, due to advances in genetic technique and sequencing technology, an increasing number of variants causing monogenic obesity has been described, mostly genes encoding components of leptin-melanocortin pathways. The accessory protein MRAP2 (Melanocortin Receptor Accessory Protein 2) acts in body weight regulation and its inactivation is associated with early-onset severe obe...

Introduction: Childhood obesity has an increasing incidence around the world, including in Brazil. There are reports of higher psychological alterations in patients with obesity. Aims: To evaluate the frequency of depression in teenagers with obesity, associating with their caloric ingestion. Methods: This is a transversal study, with teenagers ranging from 11 to 17 chronological age (CA), from both biological sexes, with obesity (zBMI>+2SD, WHO, 2007). Val...