Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

impe0096p143 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | IMPE2023

Ovarian cell dysfunction at diagnosis in girls with haematological malignancies

Lopez Dacal Jimena , Prada Silvina , Arcari Andrea , Freire Analia , Gryngarten Mirta , Gabriela Ropelato Maria , Gabriela Ballerini Maria , Eugenia Rodriguez Maria , Gutierrez Marcela , Soria Marcela , Morán Lorena , E. Ferraro Cristina , Bedecarrás Patricia , Drelichman Guillermo , Aversa Luis , Bergadá Ignacio , A. Rey Rodolfo , P. Grinspon Romina

Introduction: Haematological malignancies represent the most frequent childhood cancer. Little is known about small ovarian follicle function at diagnosis in girls with acute lymphoblastic leukaemia (ALL), acute myeloid leukaemia (AML) or non-Hodgkin lymphoma (NHL). AMH is a useful marker of small follicles.Aim: To determine small ovarian follicle status at diagnosis and after 3 months of chemotherapy in girls and adoles...