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impe0096fc3.4 | Endocrinology of Sex Differences 1 | IMPE2023

The combination of FSH and markers of Sertoli cell function provides a high accuracy strategy to differentiate central hypogonadism from constitutional delay of puberty in boys: a longitudinal prospective study.

Castro Sebastián , Correa Brito Lourdes , Bedecarrás Patricia , Gabriela Ropelato María , Keselman Ana , Cassorla Fernando , Bergadá Ignacio , A Rey Rodolfo , P Grinspon Romina

Constitutional delay of puberty (CDP) and congenital central hypogonadism (CH) show great overlap in clinical features and in gonadotrophin and testosterone serum concentrations in boys. The gold standard to distinguish both entities relies on the assessment of pubertal stage beyond 18 years of age. The long lasting insufficient FSH activity in boys with congenital CH may result in lower AMH and inhibin B serum concentrations compared with boys with CDP....

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impe0096p143 | Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology | IMPE2023

Ovarian cell dysfunction at diagnosis in girls with haematological malignancies

Lopez Dacal Jimena , Prada Silvina , Arcari Andrea , Freire Analia , Gryngarten Mirta , Gabriela Ropelato Maria , Gabriela Ballerini Maria , Eugenia Rodriguez Maria , Gutierrez Marcela , Soria Marcela , Morán Lorena , E. Ferraro Cristina , Bedecarrás Patricia , Drelichman Guillermo , Aversa Luis , Bergadá Ignacio , A. Rey Rodolfo , P. Grinspon Romina

Introduction: Haematological malignancies represent the most frequent childhood cancer. Little is known about small ovarian follicle function at diagnosis in girls with acute lymphoblastic leukaemia (ALL), acute myeloid leukaemia (AML) or non-Hodgkin lymphoma (NHL). AMH is a useful marker of small follicles.Aim: To determine small ovarian follicle status at diagnosis and after 3 months of chemotherapy in girls and adoles...

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IMPE Abstracts

The combination of FSH and markers of Sertoli cell function provides a high accuracy strategy to differentiate central hypogonadism from constitutional delay of puberty in boys: a longitudinal prospective study.

Ovarian cell dysfunction at diagnosis in girls with haematological malignancies

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