IMPE Abstracts

Diabetes insipidus (DI) is characterized by polydipsia and polyuria with a dilute urine. Central DI (CDI) results from a deficiency of arginine vasopressin (AVP) and may be due to congenital or acquired causes, the latter include tumors affecting the hypothalamic-pituitary region. Thirst acts as a central biological backup mechanism in the absence of AVP, allowing plasma osmolarity to remain stable. We describe ADI patients with hypothalamic damage, who lose the ability to per...

Introduction: Intracranial germ cell tumors (iGCTs) are rare neoplasms that mainly affect adolescents and young adults. iGCTs are divided into germinoma and non-germinomatous germ cell tumors. The hypothalamic-pituitary region is the second primary site of iGCTs after the pineal region. The iGCTs with isolated pituitary stalk involvement are rare and difficult to diagnose. They should be suspected when there is a pituitary stalk thickening >6.5 mm or a coex...