IMPE Abstracts

Introduction: Acne vulgaris affects up to 87% of adolescents. Isotretinoin is the most effective therapy for moderate to severe acne. As adverse effects of isotretinoin have been reported elevated aminotransferases (ALT and AST), hypertriglyceridemia and hypercholesterolemia. A classic dose isotretinoin (0.5-1 mg/kg/day), approximately 20% of patients develop hypertriglyceridemia and hypercholesterolemia.Objective: To de...

Introduction: The prevalence of vitiligo in the general population is 0.5 to 1%. Children under 12 years represent 23% of the patients with vitiligo. The most common type of vitiligo (85% of total) is the non-segmental. The prevalence of autoimmune thyroid disease in patients with non-segmental vitiligo is greater than the one reported in the general population. Hypothyroidism is the most common disorder seen in children with non-segmental vitiligo. Early diag...

Introduction: Epilepsy is the most common neurological disorder that requires prolonged medication in children, with a prevalence of 0.5 to 1%. Carbamazepine is one of the most prescribed antiepileptic by neuropediatricians. The administration of carbamazepine is associated with decreased free thyroxine (FT4) levels being variable the relationship with thyrotropic hormone (TSH) values. When discontinuing therapy with carbamazepine, serum thyroid hormone levels...