Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

impe0096p7 | Adrenals and HPA Axis | IMPE2023

Cortisol Stimulation Tests are Safe and Necessary for Diagnosing Central Adrenal Insufficiency

Peduti Halah Mariana , Carolina Maia Teodózio Ana , Casale Aragon Davi , Conde Lamparelli Elias Paula , de Castro Margaret , Custodio Moreira Ayrton , Roberto Rauber Antonini Sonir

Introduction: Measuring peak plasma cortisol after pharmacological stimulation induced by insulin tolerance test (ITT) and glucagon (GST) is often necessary to confirm or rule out the diagnosis of Central Adrenal Insufficiency (CAI). However, cortisol concentration cutoffs are still controversial, and these tests may result in adverse effects.Objectives: In patients who underwent ITT and glucagon test, to evaluate: the c...

impe0096ep44 | GH and IGFs | IMPE2023

GH Stimulatory Tests for Diagnosing Isolated GH Deficiency

Carolina Maia Teodózio Ana , Peduti Halah Mariana , Casale Aragon Davi , Lamparelli Elias Paula , de Castro Margaret , Custódio Moreira Ayrton , Roberto Rauber Antonini Sonir

Introduction: GH peak after GH stimulatory tests (GHST) diagnoses GH deficiency (GHD).Aims: To identify GH peak cutoff best discriminating GHD and non-GHD short stature (SS) patients.Methods: 901 children (0-18 yrs) were submitted to 1348 GHST between 2001 and 2016. We selected 458 patients suspected to have isolated SS (ISS= isolated GHD, familial SS, idiopathic SS) or GHD+ hypopi...