Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

impe0096p153 | Thyroid | IMPE2023

Establishment and verification of pediatric thyrotrophin and thyroid hormones reference intervals using indirect methods.

Ethel Zaidman Veronica , Chaler Eduardo , Dujovne Noelia , Gazek Natalia , Pelanda Melina , Garin Gomez Sabrina , Lopez Micaela , Ciaccio Marta , Manuel Lazzati Juan

Introduction and aim: Establishing reference intervals (RI) is particularly problematic for constituents with a large diversity of existing biological variation and inter-population differences, as is observed for thyroid hormones and TSH. An alternative to this problem is to use indirect methods, with a large data pools base of results. Analyze thousands of subjects including some pathologic results is statistically stronger than 120 subjects that assume heal...

impe0096p10 | Adrenals and HPA Axis | IMPE2023

Cortisol response in Non-Classic Congenital Adrenal Hyperplasia

Victoria Lobo de la Vega María , Celeste Mattone María , Marino Roxana , Manuel Lazzati Juan , Zaidman Verónica , Perez Garrido Natalia , Pelanda Melina , Balbi Viviana , César Ramírez Pablo , Belgorosky Alicia , Ciaccio Marta , Guercio Gabriela , Costanzo Mariana

Background: Non-classic forms of Congenital Adrenal hyperplasia (NCCAH) due to 21-hydroxylase deficiency are usually associated with variable degrees of postnatal androgen excess but adequate cortisol and aldosterone production. However, few studies have evaluated cortisol response.Aim: to describe the clinical, biochemical characteristics, and cortisol response to Corticotropin test in a cohort of patients with NCCAH st...