IMPE Abstracts

Mitotane (o, P'–DDD) is the drug of choice for adrenocortical carcinomas (ACC) and its measurement in plasma is essential to control drug administration.Objective: To develop and validate a simple, reliable and straightforward method for Mitotane determination in plasma samples.Method: Drug free plasma samples were collected in potassium-ethylenediamine tetraacetate (K-EDTA) tub...