IMPE Abstracts

Cumulative lifetime incidence and prevalence of endocrine abnormalities after treatment of childhood cancer increases, particularly after high-risk regimes. Both men and women experience gonadal toxicity with reduced fertility. Effects of chemotherapy and /or radiation exposure will focus on adverse effects of treatment on gonadal function, assessment of gonadal status, options for fertility preservation (FP) and risks associated with gonadal dysfunction and its treatment. For...

Introduction: Neonatal hyperthyroidism is a rare condition frequently caused by the transplacental passage of TSH receptor antibodies (TRAb) from mothers affected by Graves’ disease (GD). Hyperthyroidism may occur in 1 to 8% of children born to women with this condition. The effects of maternal hyperthyroidism in the foetal developing brain are known to have deleterious effects. After birth, neuropsychological manifestations of overt hyperthyroidism are ...