IMPE Abstracts

Introduction: The prevalence of Metabolic Syndrome (MetS) is estimated to be 4.2% to 6.4% among American children and 5.4% to 5.8% in Korean children and adolescents, according to the modified criteria of the National Cholesterol Education Program, Adult Treatment Panel III (NCEP-ATP III).

Objective: We dont have data about this syndrome in our country, because of that we consider this abstract.

Results: We included children under 18 years of age with a diagnosis of overweight or obesity, according to body mass index, if the BMI was above the 95^th percentile, it is considered obese and if it is between 85 and 95, it is considered overweight. Among 138 subjects the overall prevalence of MetS was 18.7% (30% in male and 35% in female subjects; P=0.021). The contributing factors of MetS, abdominal obesity, hyperglycemia, high blood pressure, hypertriglyceridemia, and low HDL-C, were observed in 14.3%, 4.0%, 32.0%, 25.7%, and 15.0% of the subjects, respectively. The female subjects had a higher prevalence of high blood pressure and low HDL-C than the male subjects. We found the average age was 11.9 years, the average abdominal circunference was 87.98 cm. The average uric acid value was 3.79 g/dl, similar to other studies.

Conclusion: We developed reference ranges of serum UA percentiles and quartiles for this specific poblation. The present study has confirmed the association between the highest quartiles of serum UA and increased risks for MetS and its components. These results confirm that hyperuricemia might be valuable in predicting MetS in this population. In the future, large-scale clinical trials are required to determine whether lowering UA levels can prevent and treat abdominal obesity, low HDL-C, and MetS.