Scientific Programme & Abstracts from the International Meeting in Pediatric Endocrinology (IMPE)

impe0096p37 | Diabetes and Insulin | IMPE2023

Physical fitness and compliance of ADA/ISPAD Clinical Guideline Goals among children and adolescents with type 1 diabetes: the Diactive-1 Study

J. Chueca Maria , Huerta Nidia , Andrés Carlos , Berrade Sara , Burillo Elisabet , Francisco Laura , Herrero Sara , García-Hermoso Antonio

Up to 45% of youth with type 1 diabetes (T1D) have cardiovascular (CV) risk factors and may develop subclinical cardiovascular disease in the first decade of diagnosis. Physical fitness in youth have been shown to be associated with cardiometabolic risks factors among youths with and without diabetes.Aim: To examine the association between handgrip strength and cardiorespiratory fitness and the compliance of the ADA/ISPAD clinical guidel...

impe0096p38 | Diabetes and Insulin | IMPE2023

Single Nucleotide Polymorphism +276G>T of ADIPOQ gene and the occurrence of Associated Autoimmune Diseases in children and adolescents with Type 1 Diabetes Mellitus

Usatiuc Lia-Oxana , Szabo Csilla-Eniko , Creț Victoria , Sorin Șerban Radu , Victor Pop Ioan

Background: Type 1 diabetes mellitus (T1DM) and autoimmune diseases, such as autoimmune thyroiditis (AT) or coeliac disease (CD) frequently occur together. Adiponectin is the most abundant circulating adipokine that plays a key role as an insulin-sensitizing protein in metabolic diseases. Autoimmune diseases are associated with decreased levels of adiponectin, previous studies suggesting that adiponectin may be related to disease activity and/or severity in su...

impe0096p39 | Diabetes and Insulin | IMPE2023

Implementation of an advanced hybrid closed-loop system (MiniMed 780G) in children and adolescents with type 1 diabetes, in a national diabetes training center.

Gómez Susana , Forero Catalina , Durán Paola , Cespedes Camila

Introduction: The optimal control of type 1 diabetes mellitus (DM1) has been a challenge over time, especially in the pediatric population. A high proportion of patients do not achieve glycemic targets, which has led to the search for new strategies to optimize metabolic control. Recently, advanced hybrid closed-loop system (AHCL) have been designed to combine automated basal insulin delivery with automated five-minute correction boluses integrated to continuo...

impe0096p40 | Diabetes and Insulin | IMPE2023

Type 1 diabetes mellitus incidence in Chilean children between 2006 and 2021: significant increase during the COVID-19 pandemic years.

Tampe Ingeborg , Garfias Carolina , Borzutsky Arturo , Slaibe Lisset , Garcia Hernan

Objective: Type 1 diabetes mellitus (T1D) incidence in children varies across regions and countries. A large incidence increase has been observed in several countries during the COVID-19 pandemic. The objective of this study is to determine the trends in T1D incidence rates in Chilean children between 2006 and 2021, and specifically evaluate the effect of COVID-19 pandemic in this population.Methods: We reviewed mandator...

impe0096p41 | Diabetes and Insulin | IMPE2023

Sarcopenia in adolescents with diabetes mellitus

Angel Blanco Miguel , Altamirano Nelly , Valderrama Alejandro , Calzada Raul

Objective: To describe the appendicular skeleton strength (ASS) and the associate factors in adolescent with diabetes mellitusMethodology: Cross-sectional study in puberal patients (9 to 18 years) with DM. By means of clinical records review, we corroborated demographic, auxology and biochemical variables as well as the presence or not of complications. Body Satisfaction Discomfort (BSD) was evaluated using Stunkard silh...

impe0096p42 | Diabetes and Insulin | IMPE2023

A comparative study of dental caries in children and adolescents with or without diabetes; an observational study in AbuDhabi, UAE

Elbshari Shahd , Hassan Beck Rasha , Hassan Beck Reem , Afrooz Imrana , Al Qahtani Nabras , Gupta Kowshik , Deeb Asma

Introduction: Dental caries carries a high global prevalence particularly in children and adolescents with diabetes. Salivary flow rate and glucose levels have been implicated in the higher prevalence. However, some studies show controversial results of lower dental caries in children with diabetes compared to healthy children. There is lack of data on this topic in the Arab region where both diabetes and dental caries are common. We aim to compare the prevale...

impe0096p43 | Diabetes and Insulin | IMPE2023

POC1A gene defect in two unrelated cases with severe dyslipidemic insulin resistance and SOFT syndrome

Esnaola Azcoiti María , Keselman Ana , Sanguineti Nora , Crespo Carolina , Krochik Gabriela , Costanzo Mariana , Scaglia Paula , Izquierdo Agustín , Tonietti Miriam , Verónica Aráoz Hilda , Pablo Gravina Luis , Braslavsky Débora , Casali Bárbara , Villegas Florencia , Correa Lourdes , Gabriela Obregón María , Arberas Claudia , Rey Rodolfo , Bergadá Ignacio , Noemí Alonso Cristina , Ropelato Gabriela

Introduction: SOFT syndrome (MIM#614813), denoting Short stature, Onychodysplasia, Facial dysmorphism, and hypoTrichosis, is a rare primordial dwarfism syndrome encompassing severe growth failure of prenatal onset, craniofacial dysmorphism, sparse hair, and digital abnormalities associated with biallelic pathogenic POC1Agene variants. Phenotypic spectrum has recently been expanded to include insulin resistance (IR) and muscle cramps.<p class="abst...

impe0096p44 | Diabetes and Insulin | IMPE2023

Long-term trends of pediatric type 1 diabetes incidence in Japan: before and during the COVID-19 pandemic years (1999–2021)

Matsuda Fumika , Itonaga Tomoyo , Maeda Miwako , Ihara Kenji

Background: The incidence of type 1 diabetes has increased worldwide whereas a long-term trend for pediatric type 1 diabetes has remained elusive in Japan. Because a nationwide registry system for pediatric type 1 diabetes has not been established in Japan, it is difficult to simply extrapolate a national epidemiological study from the MAPChD data in Japan. The local registry systems in each prefecture or small-scale adjacent areas would be better for extracti...

impe0096p45 | Diabetes and Insulin | IMPE2023

Evaluation of The Prevalence of Attention Deficit Disorder and Hyperactivity in Pediatric Patients with Type 1 Diabetes Mellitus Using Carbohydrate Counting

Luiza Lelot Ana , Greghi Juliana , Cristiane de Souza Mirella , Costa Figueiredo Carolina , Michelle Evangelista de Araújoi Nara , de Fátima Tonetto Fernandes Vânia , de Aguiar Pacheco Luciana , Kato Tatiana , de Paula Colares Neto Guido

Introduction: One of the pillars of type 1 diabetes mellitus (T1DM) treatment is nutritional management with carbohydrate counting (CC), which requires constant control of food consumed, learning mathematical reasoning, or using mobile apps to calculate the amount of insulin administered before meals. CC can be hampered by Attention Deficit Disorder and Hyperactivity Disorder (ADHD), characterized in childhood by hyperactivity, impulsivity, and inattention.</p...

impe0096p46 | Diabetes and Insulin | IMPE2023

IMPACT of Type of Treatment on Health-Related Quality of Life in Children and Adolescents with T1D. A Multicenter Study in LIMA, Perú

Julissa Angulo Barranca Mónica , Paola Alegre Pariona Sheyla , Claudia Aramburú Miranda Nátaly , Cecilia Bonilla Suárez Ana , Maricela Martinez Peralta Melissa , Pinto Paz Cecilia , Scerpella Crespo Luciana , Isaias Angulo Quispe Alejandro

Type 1 Diabetes Mellitus (T1D) is a chronic illness that impacts the quality of life (QoL) of patients and their families. Currently, different methods exist that facilitate glycemic control and insulin administration to achieve good metabolic control, which may contribute to a better QoL. Perú is a middle-income country with low prevalence of T1D and low access to diabetes technology. We evaluated the QoL in children and adolescents with T1D using different methods of ...