IMPE2023 Poster Presentations Sex Differentiation, Gonads and Gynaecology, and Sex Endocrinology (19 abstracts)
Argentinian Transgender Children and Adolescents Cohort: an Eight Year Observational Multicenter Study
Veronica Figueroa Gacitúa 1 , Carmen Riu 2 , Mariela Esposito 3 , Gabriela Rojas 4 , Magdalena Rodriguez saa 1 , Fernanda Carballo 2 , Verónica Gonzalez 3 , Nicolas Biancofiore 4 , Kelly Maury Fuentes 1 , Veronica Forclaz 4 , Analia Morin 3 & Veronica Fernandez Mentaberry 2
1Hospital de Niños Pedro de Elizalde, Buenos Aires, Argentina. 2Hospital General de Agudos Carlos G Durand, Buenos Aires, Argentina. 3Hospital de Niños Sor Maria Ludovica, La Plata, Argentina. 4Hospital Nacional Profesor Alejandro Posadas, El Palomar, Argentina
Introduction: Transgender and gender–diverse (TGD) individuals do not fully identify with the gender assigned at birth. Argentina has approved in 2012 a pioneer gender identity law (N° 26.743) which depathologize this condition and guarantees access to medical care of TGD individuals. In recent years, there has been a significant increase in the number of youth seeking gender-affirming medical interventions leading to the creation of multidisciplinary care teams in order to respond to the growing demand.
Aim: to describe different aspects of the largest Argentinian TGD children and adolescents cohort
Materials and methods: retrospective, observational, multicenter cohort study, including 312 TGD children and adolescents admitted at 4 Hospitals from Buenos Aires, Argentina from 2014 to 2022.
Results: 247 transmale (TM) and 65 transfemale (TF) were included (ratio TM:TF 3.8:1). Mean age for TM was 14.7 +/- 2.26 and for TF 14.7+/-2.9 years. Mean chronological age at first perception was 8.8 +/-3.3 years for TM and 8.6 +/-4.2 for TF, mean chronological age for social transition was 12.6 +/-2.3 for TM and 12.4 +/-4 years for TF. Nutritional aspect: 40.96% (n=93) of TM and 30% (n=18) of TF were obese or had overweight; 6.5% (n=16) of TM and 3% (n=2) of TF had eating disorders; 25 hydroxivitamin D deficiency was found in 88.66% (n=203) of the total population. Psychological comorbidities including anxiety, depression, panic attacks and psychosis among TGD were present in 27.5% (n=86). Mean Basal BMD Z score was 0.13 +/- 0.97 in TM and -1.05 +/- 0.97 in TF. GnRh analogs were started in 94 TM at a mean age of 13.9 +/-2 years and in 33 TF at 15.7 +/-1.75. Gender-affirming hormone treatment was started in 84 TM at a mean age of 16.3 +/-1.17 and in 29 TF at 16.6 +/-0.99. Progestagen was used in 7.3% (n 18) and breast surgery was performed in 8% (n=20) of TM.
Conclusions: Among individuals of our cohort we found a higher prevalence of Transmen and a large percentage of obesity, overweight, vitamin D deficiency and psychological comorbidities. These findings support the fact that the optimal model of care for TGD children and adolescents involves a coordinated multidisciplinary team approach. To our knowledge this is the largest Argentinian cohort study describing different aspects of TGD children and adolescents.
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