IMPE Abstracts

Introduction: Vast majority of children and adolescents with adrenocortical tumor (ACT) present clinical signs of androgen excess. Long-term exposure to sex steroids can activate the GnRH pulse generator and trigger central precocious puberty, as shown in treated 21-hydroxilase deficiency, McCune-Albright syndrome and testotoxicosis. ACTs are rare in pediatric patients and, therefore, the knowledge about characteristics of pubertal outcome after tumor resectio...

Introduction: Most children and adolescents with adrenocortical tumor (ACT) present increased height age, advanced bone age and compromised predicted adult height at the time of diagnosis. Growth pattern after tumor resection and adult height data are scarce in the literature. We present a cohort of 63 completed growth patients followed in a single center of Southern Brazil.Methods: Retrospective evaluation of patients t...